ABSTRACT
We aimed to provide scientific evidence for the effective control of the epidemic and to investigate the sources of infection and possible ways of transmission.Epidemiological investigation was carried out to explore the source of infection by using the case-control study.Results showed that the outbreak of the epidemic was hemorrhagic fever,the onset of 40 cases was from August 21 to September 4,accounting for 73.68 ％ of the case number.Cases were cluster in Weizhuang Town,Feinan Town and Longkang Town,accounting for 60.00％ of the case number.The cases who aged from 40 to 79 years accounted for 85.00％.The cases with medium and high fever,tiredness,chills,muscle pain,gastrocnemius and headache accounted for 85.00％,95.00％,90.00％,75.00％,62.50％ and 40.00％,respectively.The 97.50％ cases had exposure history of suspected contaminated water.Case-control study result showed that hands and feet had the wound in 15 days before the onset (x2=15.74,P ＜0.01),and farming work in 15 days before the onset (x2 =11.08,P ＜0.01) were the risk factors of leptospirosis infection.There are the bacteria change and the trend from south to north along the Huaihe River Basin.Strengthen the monitoring work in high-risk areas was the effective measurement to reduce the incidence of leptospirosis.